Fluidics
Next-Generation Sequencing
Strengthen Your Instrument with IDEX Health & Science Fluidic Components
Precise, repeated cycling of reagents can be a challenge for conventional fluid handling instruments. Partnering with IDEX Health & Science on the development of your next-generation sequencing (NGS) platform ensures you have a reliable custom solution that delivers accurate reagent flow with consistent valve timing. Our integrated approach to fluidic architecture incorporates a valve-on-manifold for compact design, reduced reagent waste, and easy system integration with minimal connection points. Complete subsystems offer piercing probes for reagent sampling and dispensing, degassers to ensure stable optical detection, and pressure sensors to provide diagnostic system information.
Our 60 years of fluidic engineering expertise, computational modeling, and performance testing tools ensure that your NGS system generates high quality sequencing data with maximum uptime and system-to-system reproducibility.
IDEX Health & Science specializes in taking complex concepts to reality. We partner with you to remove the risks in controlling reagents, optimizing samples, and designing unique fluidic pathways, turning your theory into working solutions that advance science.
- We are experts in manipulating fluids, controlling dynamic flow performance, and optimizing the overall user experience for instrument consistency
- Achieve predictability and minimize project risk through advanced modeling, computational simulation, and testing
- Reliably solve challenges before they disrupt your instrument schedule
Download our Next-Generation Sequencing Fluidics Guide
Click the icons below to learn about each of the fluidic components in a next-generation sequencer.
Valves
Manifolds
Sensors
Degassers
Probes
Tubing
Switching Valves
Reagent Selection with Certainty
Elevate your complex flow path with a switching valve (also known as a rotary valve) customized to your needs. A single rotary valve can control up to 24 reagents with ease and negligible reagent crossover concerns. Valves are fully biocompatible and can be offered as standalone components or integrated onto a manifold assembly to meet the specific needs of your unique design.
Manifold Assemblies and Subsystems
Streamline Your Complex Fluidics
Our design team works with you to develop an optimized manifold assembly for your unique fluidic system. IDEX Health & Science manifolds provide a reliable, easily serviceable, consolidated fluid path. With multi-layer manifolds and multiple material options, design possibilities are endless. Integration can include tubing and fittings, probes, valves (rotary and solenoid), pumps, degassers, and sensors.
Learn More about our Manifold Assembly and Subsystem Capabilities
Sensors
Gain Confidence Under Pressure
Inline pressure sensors monitor system performance, providing real-time diagnostic feedback to flow anomalies. The extremely low internal volume and a fully encapsulated MEMS sensor can be integrated standalone or mounted to a fluidic manifold for front-end or back-end flow monitoring inside your NGS system.
Degassers
Maintain Clear Consistency
The presence of bubbles in a fluidic line can disrupt the precision and accuracy of your NGS system. Incorporating a degasser into the stream provides trouble-free operation, ensuring the fluidic system is free of air bubbles by actively removing dissolved gases that interfere with optical detection and hamper flow precision. Options are manifold mountable or standalone with a vacuum pump assembly.
Probe Assemblies
Get Peak Performance and Superior Precision
PEEK probes provide both the strength required for repetitive use and the biocompatibility you desire for your system. With several tip geometries available, your sampling and dispensing needs will be fully met with our probes at an economical price point.
Tubing Assemblies
Reduce Complexity in Changing Conditions
We offer a comprehensive line of biocompatible tubing and connection options that meet the demanding requirements of today’s high-performance NGS systems. As a manufacturer of tubing and connections, IDEX Health & Science is uniquely positioned to help you integrate your tubing into kits and assemblies for the simplified installation and serviceability of your platform. We cut, form, produce, test, and label every piece, so you receive a single assembly that’s ready to integrate directly into your system.
What is the optimal configuration for my Next Generation Sequencing fluidics design?
Review our FAQs on configuring your fluidics for NGS
Semrock Avant™ Filter Set Family to Complement Your Fluidics
Amplify Your Fluorescence Performance with Popular Probes
Our Avant Filter Set Family delivers improved fluorescence signal and signal-to-noise ratio to NGS systems that prioritize efficiency, speed, and performance in single-band filter sets.
Avant Sets Available Now
- YFP / Venus
- Cy3 / Alexa Fluor™ 555
- Texas Red® / Alexa Fluor™ 594
- Cy5.5 / Alexa Fluor™ 680
- Alexa Fluor™ 700
- Cy7 / Alexa Fluor™ 750
- Alexa Fluor™ 546
- Cy5 / Alexa Fluor™ 647
Learn more about our Avant™ filter set family
Partner with IDEX Health & Science
If you’re ready to make your visions a reality, contact us and we’ll show you how to take your company to the next level.
Let's Discuss Your Next-Generation Sequencing Application