How can you improve the throughput of your flow cell analysis? Throughput of fluorescence based instrumentation is often constrained by the speed at which a sample can be illuminated. Imaging the entire area requires multiple “step and shoot” scans be stitched together to cover the entire sample area.
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How do you handle customized fluidic design iterations when you are on a tight timeline and budget? In fluidic pathway development, the most efficient way to optimize your system is to integrate a manifold to reduce device size, decrease leaks, and add valves and pumps. This will improve reliability of the flow path and provide consistent performance.
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Last week, our IDEX Health & Science Melles Griot team members moved into the new IDEX Health & Science Center of Excellence. Our Optical Center of Excellence (COE) is a brand new, state-of-the-art facility in Rochester, NY.
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Hello and welcome to the IDEX Health & Science insights blog. We will be featuring a variety of posts ranging from technical content and trending industry news to our community engagement efforts. We will also be highlighting the people behind the scenes here who make this a great business to partner with.
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Are you developing a life science instrument under a tight budget and aggressive timeline, with technical needs that push optical performance boundaries?
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Dr. Na Ji is a group leader at the Howard Hughes Medical Institute’s Janelia Research Campus, a pioneering research center focused on neuroscience and imaging. A neurobiologist with a background in chemical physics, she develops adaptive optical methods to improve in vivo imaging and applies these methods to the structural and functional imaging of neural circuits. Check out our interview with her on her work and use of Semrock optical filters.
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Semrock’s Multiphoton LaserMUX beam combiners enable deeper tissue imaging and improved contrast in multi-color and multi-modal fluorescence microscopy. The filters set new performance standards by simultaneously achieving high transmission, high reflection, and low GDD over both reflection & transmission, while maintaining minimal wavefront distortion. Ideal for combining two femtosecond pulsed laser beams, they are perfect for optogenetics and other life science applications.
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Silas Leavesley, Ph.D., is an associate professor of Chemical and Biomolecular Engineering and a member of the Center for Lung Biology at the University of South Alabama. His research focuses on the development of optical imaging and illumination technologies for use in novel biomedical and clinical imaging applications. Leavesley is co-founder of SpectraCyte, a startup business aimed at providing a next-generation gastrointestinal endoscope.
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Jennifer Ross is an award-winning biophysicist, principal investigator at Ross Laboratory at University of Massachusetts Amherst. In the Ross Lab, she studied the microtubule cytoskeleton and its effect on cellular processes. Learn more about her work in this interview.
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Chris Schaffer is an associate professor in the Meinig School of Biomedical Engineering at Cornell University. He co-runs Cornell’s Schaffer – Nishimura Lab, which develops advanced optical techniques that enable the study of neurological disease through quantitative imaging and manipulation of cells.
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